Side effect by weight loss surgery

June 12, 2006

According to new research presented at 66th Scientific Session of American Diabetes Association (ADA) the Bariatric weight loss surgery may affect bone health after some times.

The main effect of weight loss surgery is found by Robert Considine, PHD assistant professor with its associates and examined that it effect on serum makers of bone. He said the long term effect of weight loss surgery must be investigated.

At baseline and at 6 months after surgery, the researchers measured levels of serum osteocalcin, bone-specific alkaline phosphatase (BAP), and N-telopeptide cross-linked collagen type 1 (NTX), which are indicative of bone resorption

The bariatric surgery increased to 3.5 from 2.4 per 100,000 in USA from 1996 to 2002. After 6 months of surgery the level of serum osteocalcin(6.87 vs 10.87 ng/mL; P < .0001), BAP (14.16 vs 16.43 ng/mL; P = .04) and NTX (10.91 vs 19.62 nM/BCE; P < .0001) measured by researchers, which are indicative of bone resorption. However circulating level of calcium and phosphate remains unchanged after surgery.

The researcher will measured serum bone maker again after 1 year for future studies.

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